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・ Surface integral
・ Surface integrity
・ Surface irrigation
・ Surface layer
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・ Surface lift
・ Surface lure
・ Surface mail
・ Surface map
・ Surface marker buoy
・ Surface metrology
・ Surface micromachining
・ Surface mining
・ Surface Mining Control and Reclamation Act of 1977
・ Surface modification
Surface modification of biomaterials with proteins
・ Surface movement radar
・ Surface Ocean Lower Atmosphere Study
・ Surface of class VII
・ Surface of constant width
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Surface modification of biomaterials with proteins : ウィキペディア英語版
Surface modification of biomaterials with proteins

Biomaterials are materials that are used in contact with biological systems. Biocompatibility and applicability of surface modification with current uses of metallic, polymeric and ceramic biomaterials allow alteration of properties to enhance performance in a biological environment while retaining bulk properties of the desired device.
Surface modification involves the fundamentals of physicochemical interactions between the biomaterial and the physiological environment at the molecular, cellular and tissue levels (reduce bacterial adhesion, promote cell adhesion). Currently, there are various methods of characterization and surface modification of biomaterials and useful applications of fundamental concepts in a several biomedical solutions.
==Function==

The function of surface modification is to change the physical and chemical properties of surfaces to improve the functionality of the original material. Protein surface modification of various types biomaterials (ceramics, polymers, metals, composites) is performed to ultimately increase biocompatibility of the material and interact as a bioactive material for specific applications. In various biomedical applications of developing implantable medical devices (such as pacemakers and stents), surface properties/interactions of proteins with a specific material must be evaluated with regards to biocompatibility as it plays a major role in determining a biological response. For instance, surface hydrophobicity or hydrophilicity of a material can be altered. Engineering biocompatability between the physiological environment and the surface material allows new medical products, materials and surgical procedures with additional biofunctionality.
Surface modification can be done through various methods, which can be classified through three main groups: physical (physical adsorption, Langmuir blodgett film), chemical (oxidation by strong acids, ozone treatment, chemisorption, and flame treatment) and radiation (glow discharge, corona discharge, photo activation (UV), laser, ion beam, plasma immersion ion implantation, electron beam lithography, and γ-irradiation).

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